Under the application background of interference search in space-based positioning system based on light Unmanned aerial vehicle （UAV）-platform， the implementation mechanism of multi-platform time difference positioning （TDOA） is analyzed in detail. In order to solve the problem of UAV group arriving at the optimal positioning area quickly before TDOA location， and then realizing effective positioning， a TDOA positioning solution based on received signal strength （RSS） positioning auxiliary information is proposed， and the whole positioning process and key scenarios are described in detail. Through the feasibility demonstration of the method and the analysis of the positioning performance， it is concluded that this method can make the maximum time of the whole positioning process controlled within a continuation cycle of the unmanned machine， under the premise of the smooth implementation of the automation of the positioning process.