In order to solve the problem that the multi-screen video display system cannot adapt to the multi-screen transmission of ultra-high-definition （UHD） video according to the number of split screens， a heterogeneous multi-core video streaming transmission method is proposed. First， the embedded system based on ARM is used to realize multi-task processing and real-time monitoring. Then FPGA realizes hardware acceleration of receiving， converting， processing and split-screen output display of video stream. The system can configure the working parameters of FPGA according to the input signal in real time to realize the split screen display of UHD video stream with variable resolution and number of split screens. Finally， the system is tested using the Zynq UltraScale+MPSOC XCZU7EV heterogeneous multi-core processor，and results show that the multi-channel split-screen mosaic of 4K video has no obvious dislocation and consistent synchronization， which better meets the requirements of video multi-channel split-screen display.