With the development of big data， data has become a major strategic resource for countries and its social impact is increasingly obvious. Thus， data science is proposed to explore and study basic scientific problems contained in big data. In this paper， the development of big data， the rise and connotation of data science are first introduced. Second， the research status of big data and data science is analyzed， and the application of data in various industries is discussed. Third， the big data proving ground that is constructed to explore laws and problems of data science is briefly described. Finally， in order to promote the development of data science， accelerate the transformation of the real world to the digital world， and realize the intelligent life， the key issues of data science and the new thinking in digital world are discussed.